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MA5-15725 targets BLK in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples.
The MA5-15725 immunogen is purified recombinant fragment of human BLK expressed in E. Coli.
MA5-15725 detects BLK which has a predicted molecular weight of approximately 58kDa.
B-lymphoid tyrosine kinase (BLK) is a non-receptor tyrosine kinase that belongs to the Src family of kinases. BLK plays an important role in B-cell activation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase; MGC10442; p55-Blk; Tyrosine-protein kinase Blk
基因别名: BLK; MODY11
UniProt ID: (Human) P51451
Entrez Gene ID: (Human) 640