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Recommended positive controls: A549, HeLa, HepG2.
Predicted reactivity: Mouse (93%), Rat (93%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BH; Bleomycin hydrolase; BLM hydrolase
基因别名: BH; BLMH; BMH
UniProt ID: (Human) Q13867
Entrez Gene ID: (Human) 642
分子生物学功能: cysteine protease protease protein modifying enzyme