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Proteintech
BLNK Polyclonal Antibody
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产品信息
10855-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BLNK Fusion Protein Ag1290 (1-456 aa encoded by BC018906)
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDKLNKITV PASQKLRQLQ KMVHDIKNNE GGIMNKIKKL KVKAPPSVPR RDYASESPAD EEQQWSDDFD SDYENPDEHS DSEMYVMPAE ENADDSYEPP PVEQETRPVH PALPFARGEY IDNRSSQRHS PPFSKTLPSK PSWPSEKARL TSTLPALTAL QKPQVPPKPK GLLEDEADYV VPVEDNDENY IHPTESSSPP PEKAPMVNRS TKPNSSTPAS PPGTASGRNS GAWETKSPPP AAPSPLPRAG KKPTTPLKTT PVASQQNASS VCEEKPIPAE RHRGSSHRQE AVQSPVFPPA QKQIHQKPIP LPRFTEGGNP TVDGPLPSFS SNSTISEQEA GVLCKPWYAG ACDRKSAEEA LHRSNKDGSF LIRKSSGHDS KQPYTLVVFF NKRVYNIPVR FIEATKQYAL GRKKNGEEYF GSVAEIIRNH QHSPLVLIDS QNNTKDSTRL KYAVKVS (1-456 aa encoded by BC018906)
靶标信息
B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B cell adaptor containing SH2 domain; B cell linker protein; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; Cytoplasmic adapter protein; Lymphocyte antigen 57; MGC111051; SLP-65; Src homology 2 domain-containing leukocyte protein of 65 kDa; Src homology [SH2] domain-containing leukocyte protein of 65 kD
基因别名: AGM4; BASH; Bca; BLNK; BLNK-S; Ly-57; LY57; Lyw-57; SLP-65; SLP65
UniProt ID: (Human) Q8WV28, (Mouse) Q9QUN3
Entrez Gene ID: (Human) 29760, (Mouse) 17060
