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Invitrogen
BMI-1 Polyclonal Antibody
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产品信息
PA1-16973
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to an internal region within residues 1-100 of human Bmi1 [Swiss-Prot# P35226] .
偶联物
形式
Liquid
浓度
1.09 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Suggested positive control: human and mouse skeletal muscle, human skeletal muscle protein, antigen standard for BMI1 (transient overexpression lysate), mouse skeletal muscle protein.
靶标信息
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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