This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. 查看细节
Immunogen sequence: KVAEIQGHAG GRRSGQSHEL LRDFEATLLQ MFGLRRRPQP SKSAVIPDYM RDLYRLQSGE EEEEQIHSTG LEYPELP
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
蛋白别名: BMP; BMP-2B; BMP-4; Bone morphogenetic protein; Bone morphogenetic protein 2B; Bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein
基因别名: BMP2B; BMP2B1; BMP4; DVR4; MCOPS6; OFC11; ZYME
UniProt ID: (Human) P12644
Entrez Gene ID: (Human) 652
分子生物学功能: growth factor