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Bioss
BMPER Polyclonal Antibody
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产品信息
BS-6910R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human BMPER, amino acids 501-600.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP-binding endothelial regulator precursor protein; BMP-Binding Endothelial Regulator Protein; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; CRIM3; crossveinless 2; crossveinless-2; hCV2; mCV2; Protein crossveinless-2
基因别名: 3110056H04Rik; BMPER; CRIM3; CV-2; CV2; KIAA1965; RGD1563373
UniProt ID: (Human) Q8N8U9, (Mouse) Q8CJ69
Entrez Gene ID: (Human) 168667, (Mouse) 73230, (Rat) 300455
ureteric bud development
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
regulation of endothelial cell migration
negative regulation of BMP signaling pathway
endothelial cell activation
endothelial cell differentiation
inner ear development
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of ERK1 and ERK2 cascade
