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Invitrogen
BMPR1A Polyclonal Antibody
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产品信息
PA1-30185
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length protein (Human) expressed in mouse NSO cells.
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-30185 detects BMPR1A from human samples.
PA1-30185 has been successfully used in ELISA & Western blot applications.
The PA1-30185 immunogen is recombinant full length protein (Human) expressed in mouse NSO cells.
Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
靶标信息
BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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