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Invitrogen
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Peptide sequence: GGIDFKTNES DLRKFFSQYG SVKEVKIVND RAGVSKGYGF VTFETQEDAQ
Sequence homology: Cow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bol, boule-like; boule-like RNA binding protein; boule-like RNA-binding protein; Protein boule-like
基因别名: BOLL; BOULE
UniProt ID: (Human) Q8N9W6
Entrez Gene ID: (Human) 66037