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Proteintech
BORIS Polyclonal Antibody
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产品信息
11074-2-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BORIS Fusion Protein Ag1547 (361-663 aa encoded by BC130486)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Polyclonal anti-CFCFL antibody (11074-2-AP) is produced by immunizing animals with part of C-terminal chain of CTCFL and detects a 75 kDa and a 55 kDa band.
Immunogen sequence: VRSHTGERP FQCCQCSYAS RDTYKLKRHM RTHSGEKPYE CHICHTRFTQ SGTMKIHILQ KHGENVPKYQ CPHCATIIAR KSDLRVHMRN LHAYSAAELK CRYCSAVFHE RYALIQHQKT HKNEKRFKCK HCSYACKQER HMTAHIRTHT GEKPFTCLSC NKCFRQKQLL NAHFRKYHDA NFIPTVYKCS KCGKGFSRWI NLHRHSEKCG SGEAKSAASG KGRRTRKRKQ TILKEATKGQ KEAAKGWKEA ANGDEAAAEE ASTTKGEQFP GEMFPVACRE TTARVKEEVD EGVTCEMLLN TMDK (361-663 aa encoded by B C130486)
靶标信息
CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes. CTCFL is normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BORIS; BORIS like protein; BORIS-like protein; Brother of the regulator of imprinted sites; Cancer/testis antigen 27; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein)-like; CT27; CTCF paralog; CTCF T; CTCF-like protein; HMG 1L1; HMG-1L1; likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL); MGC163358; MGC169105; MGC169106; putative high mobility group protein 1-like 1; putative high mobility group protein B1-like 1; Transcriptional repressor CTCFL; Zinc finger protein CTCF-T
基因别名: BORIS; CT27; CTCF-T; CTCFL; dJ579F20.2; HMGB1L1; OTTMUSG00000016680
UniProt ID: (Human) Q8NI51, (Mouse) A2APF3
Entrez Gene ID: (Human) 140690, (Mouse) 664799
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein binding
histone binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
nucleic acid binding
C2H2 zinc finger transcription factor
regulation of gene expression by genetic imprinting
transcription from RNA polymerase II promoter
cell cycle
positive regulation of gene expression
histone methylation
DNA methylation involved in gamete generation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of histone H3-K4 methylation
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
