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Proteintech
BPNT1 Polyclonal Antibody
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产品信息
16461-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BPNT1 Fusion Protein Ag9523 (1-325 aa encoded by BC017801)
偶联物
形式
Liquid
浓度
0.16 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MASSNTVLM RLVASAYSIA QKAGMIVRRV IAEGDLGIVE KTCATDLQTK ADRLAQMSIC SSLARKFPKL TIIGEEDLPS EEVDQELIED SQWEEILKQP CPSQYSAIKE EDLVVWVDPL DGTKEYTEGL LDNVTVLIGI AYEGKAIAGV INQPYYNYEA GPDAVLGRTI WGVLGLGAFG FQLKEVPAGK HIITTTRSHS NKLVTDCVAA MNPDAVLRVG GVGNKIIQLI EGKASAYVFA SPGCKKWDTC APEVILHAVG GKLTDIHGNV LQYHKDVSHR TWPKPDFFRA QFFLESHSCF SRNFKNVSTP IKNIYDVIIY AYETDL (1-325 aa encoded by B C017801)
靶标信息
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; Bisphosphate 3'-nucleotidase 1; BPntase; BPntase 1; epididymis luminal protein 20; HsPIP; Inositol-polyphosphate 1-phosphatase; PAP phosphatase; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; RnPIP; scHAL2 analogous 3; testicular tissue protein Li 29
基因别名: BPNT1; BPntase; HEL20; PIP; Sal3
UniProt ID: (Human) O95861, (Mouse) Q9Z0S1, (Rat) Q9Z1N4
Entrez Gene ID: (Human) 10380, (Mouse) 23827, (Rat) 64473
