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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MASSNTVLMR LVASAYSIAQ KAGMIVRRVI AEGDLGIVEK TCATDLQTKA DRLAQMSICS SLARKFPKLT IIGEEDLPSE EVDQELIEDS QWEEILKQPC
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3'-phosphoadenosine 5'-phosphate phosphatase; bisphosphate 3'-nucleotidase 1; BPntase; BPntase 1; BPntase; lithium-sensitive nucleotidase; inhibited by inositol 1,4-bisphosphate; epididymis luminal protein 20; inositol-polyphosphate 1-phosphatase; PAP phosphatase; PAP-inositol-1,4-phosphatase; testicular tissue protein Li 29; unnamed protein product
基因别名: HEL20; HsPIP; PIP
UniProt ID: (Human) O95861
Entrez Gene ID: (Human) 10380