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Invitrogen
BRD8 Recombinant Superclonal Antibody (1HCLC)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 3
BRD8 Antibody (711907) in WB
Western blot analysis was performed on modified whole cell extracts (1% SDS) (30 µg lysate) of HCT 116 (Lane 1), HeLa (Lane 2), SK-BR-3 (Lane 3), Caco-2 (Lane 4), SW480 (Lane 5) and tissue extracts of Mouse testis (Lane 6) and Rat testis (Lane 7). The blot was probed with Anti-BRD8 Recombinant Rabbit Polyclonal Antibody (Product # 711907, 1:200 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A ~120 kDa band c... View More
产品信息
711907
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
1HCLC
抗原
Protein corresponding to human BRD8 [aa1-aa200]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2734796
产品详细信息
This antibody is predicted to react with Monkey, Horse, Bovine, Cat.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
靶标信息
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bromodomain-containing protein 8; p120; Skeletal muscle abundant protein; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein of 120 kDa; TrCP120
基因别名: 2610007E11Rik; 4432404P07Rik; BRD8; p120; SMAP; SMAP2
UniProt ID: (Human) Q9H0E9, (Mouse) Q8R3B7
Entrez Gene ID: (Human) 10902, (Mouse) 78656, (Rat) 291691
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
regulation of growth
histone H4 acetylation
histone H2A acetylation
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
signal transduction
cell surface receptor signaling pathway
intracellular receptor signaling pathway
