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Invitrogen
BRUNOL4 Polyclonal Antibody
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产品信息
PA5-31849
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human BRUNOL4. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.69 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: H1299, HCT116.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (97%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bruno -like 4; bruno-like 4, RNA binding protein; Bruno-like protein 4; CELF-4; CUG-BP and ETR-3 like factor 4; CUG-BP- and ETR-3-like factor 4; CUGBP; CUGBP Elav-like family member 4; LYST-interacting protein LIP9; RNA-binding protein BRUNOL-4; RNA-binding protein BRUNOL4
基因别名: BRUNOL4; CELF-4; CELF4
UniProt ID: (Human) Q9BZC1
Entrez Gene ID: (Human) 56853
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splice site selection
germ cell development
embryo development
negative regulation of translation
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
negative regulation of excitatory postsynaptic potential
