This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. 查看细节
Immunogen sequence: LLHYLYTGEF GMEDSRFQNV DILVQLSEEF GTPNSLDVDM RGLFDYMCYY DVVLSFSSDS ELVEAFGGNQ NCLDEELKAH KAVISARSPF FRNLLQRRIR TGEE
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
蛋白别名: BTB (POZ) domain containing 7; BTB/POZ domain-containing protein 7
基因别名: BTBD7; FUP1; KIAA1525
UniProt ID: (Human) Q9P203
Entrez Gene ID: (Human) 55727