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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 10
Keep as concentrated solution.
Predicted reactivity: Mouse (95%), Rat (96%), Pig (96%), Rhesus Monkey (99%), Bovine (99%).
Positive Control: Jurkat, Neuro2A, GL261, C8D30.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; Bcl-10; c-E10; CARD containing molecule enhancing NF-kB; CARD-containing apoptotic signaling protein; CARD-containing molecule enhancing NF-kappa-B; CARD-containing proapoptotic protein; CARD-like apoptotic protein; caspase-recruiting domain-containing protein; cCARMEN; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; Cellular-E10; CIPER; hCLAP; Mamm; Mammalian CARD-containing adapter molecule E10; mCIPER; mCLAP; mE10; OTTHUMP00000011647; OTTHUMP00000036080; R-RCD1; RCD; RP11-234D19.2
基因别名: AI132454; BCL-10; BCL10; c-E10; C81403; CARMEN; cE10; CIPER; CLAP; IMD37; ME10
UniProt ID: (Human) O95999, (Rat) Q9QYN5, (Mouse) Q9Z0H7
Entrez Gene ID: (Human) 8915, (Rat) 83477, (Mouse) 12042