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产品信息
MA1-22009
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
免疫组化（冰冻） (IHC (F)) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
BFL-103 |
抗原 |
Recombinant full length protein (Human). |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.7 mg/mL |
纯化类型 |
Protein A |
保存液 |
PBS |
内含物 |
no preservative |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_557784 |
产品详细信息
Recommended positive controls: tonsil/thymus.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bloom syndrome protein; Bloom syndrome, RecQ helicase-like; DNA helicase, RecQ-like type 2; MGC126616; MGC131618; MGC131620; RecQ protein-like 3; RecQ-like DNA helicase BLM; RecQ2
基因别名: BLM; BS; RECQ2; RECQL2; RECQL3
UniProt ID: (Human) P54132
Entrez Gene ID: (Human) 641
分子生物学功能:
DNA helicase
regulation of cyclin-dependent protein serine/threonine kinase activity
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA strand renaturation
DNA replication
DNA repair
DNA recombination
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
response to X-ray
protein sumoylation
replication fork processing
DNA duplex unwinding
positive regulation of transcription, DNA-templated
negative regulation of DNA recombination
replication fork protection
protein oligomerization
negative regulation of cell division
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin
regulation of signal transduction by p53 class mediator
bubble DNA binding
p53 binding
single-stranded DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
ATP-dependent helicase activity
four-way junction helicase activity
ATPase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
