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Alomone Labs, LTD
Bombesin Receptor 1 (NMBR) Polyclonal Antibody
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Bombesin Receptor 1 (NMBR) Antibody (ABR-004-200UL) in ICC/IF
Expression of Bombesin receptor 1 in a human breast cancer cell line - Immunocytochemical staining of paraformaldehyde-fixed and permeabilized mammary gland adenocarcinoma MDA-MB-231.A. Cells were stained with Anti-Bombesin Receptor 1 (NMBR) Antibody (#ABR-004), (1:1000), followed by goat Anti-rabbit-AlexaFluor-555 secondary Antibody (red).Hoechst 33342 (blue) is used to visualize the nuclei. B. Live view o... View More
产品信息
ABR-004-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KSAHNLPGEYNEHTKK, corresponding to amino acid residues 241-256 of human BB1R, 3rd intracellular loop
偶联物
形式
Lyophilized
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
NMBR, also known as neuromedin B receptor, a Bombesin Receptor, activates phospholipase and protein kinase C and enhances calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissues. Neuromedin B receptor expression has been reported in brain, particularly the olfactory bulb and thalamus, and in colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. In addition, it has been shown to be present in cancer of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bombesin receptor 1; epididymis secretory sperm binding protein Li 185a; Epididymis tissue protein Li 185a; Neuromedin-B receptor; Neuromedin-B-preferring bombesin receptor; NMB-R
基因别名: BB1; BB182387; BB1R; NMB-R; NMBR
UniProt ID: (Human) P28336, (Mouse) O54799, (Rat) P24053
Entrez Gene ID: (Human) 4829, (Mouse) 18101, (Rat) 25264
