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Invitrogen
C11orf85 Polyclonal Antibody
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产品信息
PA5-34721
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human LOC283129. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
C11orf85, also known as PCIF1 (phosphorylated CTD-interacting factor 1), is located on chromosome 11. This gene encodes a protein that plays a critical role in post-transcriptional modification and regulation processes. PCIF1 is involved in the methylation of mRNA, specifically adding a methyl group to the 2'-O position of the first nucleotide adjacent to the cap structure of mRNA. This cap-specific mRNA (nucleoside-2'-O-)-methyltransferase activity is crucial for mRNA stability, translation, and the regulation of gene expression. The PCIF1 protein also has interactions with RNA polymerase II and is involved in the maturation and processing of nascent mRNA transcripts. Studies have shown that the disruption of PCIF1 function can lead to altered RNA metabolism and has potential implications in a variety of cellular processes, including immune responses and ferroptosis resistance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK085; LOC283129; Membrane-anchored junction protein; uncharacterized protein C11orf85
基因别名: C11orf85; MAJIN
UniProt ID: (Human) Q3KP22
Entrez Gene ID: (Human) 283129
