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Abnova
C1QTNF3 Polyclonal Antibody, MaxPab™
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产品信息
H00114899-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C1QTNF3 (NP_112207, 1 a.a. approximately 246 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.35 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLWRQLIYWQ LLALFFLPFC LCQDEYMESP QTGGLPPDCS KCCHGDYSFR GYQGPPGPPG PPGIPGNHGN NGNNGATGHE GAKGEKGDKG DLGPRGERGQ HGPKGEKGYP GIPPELQIAF MASLATHFSN QNSGIIFSSV ETNIGNFFDV MTGRFGAPVS GVYFFTFSMM KHEDVEEVYV YLMHNGNTVF SMYSYEMKGK SDTSSNHAVL KLAKGDEVWL RMGNGALHGD HQRFSTFAGF LLFETK
靶标信息
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cartonectin; Collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; Complement C1q tumor necrosis factor-related protein 3; CORS26; Secretory protein CORS26
基因别名: C1ATNF3; C1QTNF3; CORCS; CORS; CORS-26; CORS26; CTRP3; UNQ753/PRO1484
UniProt ID: (Human) Q9BXJ4
Entrez Gene ID: (Human) 114899
cellular triglyceride homeostasis
negative regulation of NF-kappaB import into nucleus
fat cell differentiation
negative regulation of gluconeogenesis
positive regulation of cytokine secretion
negative regulation of inflammatory response
positive regulation of adiponectin secretion
protein trimerization
negative regulation of monocyte chemotactic protein-1 production
negative regulation of interleukin-6 secretion
