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Bioss
C1orf86 Polyclonal Antibody
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产品信息
BS-15079R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human C1orf86, amino acids 101-180.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FANCA-associated protein of 20 kDa; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86)
基因别名: C1orf86; FAAP20; FP7162
UniProt ID: (Mouse) Q3UN58, (Human) Q6NZ36, (Rat) D4AAA5
Entrez Gene ID: (Mouse) 67513, (Human) 199990, (Rat) 362678
