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Proteintech
C1qA Polyclonal Antibody
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产品信息
11602-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C1qA Fusion Protein Ag2141 (1-245 aa encoded by BC030153)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is raised against C1qA which is the A-chain polypeptide of human complement subcomponent C1q.
Immunogen sequence: MEGPRGWLV LCVLAISLAS MVTEDLCRAP DGKKGEAGRP GRRGRPGLKG EQGEPGAPGI RTGIQGLKGD QGEPGPSGNP GKVGYPGPSG PLGARGIPGI KGTKGSPGNI KDQPRPAFSA IRRNPPMGGN VVIFDTVITN QEEPYQNHSG RFVCTVPGYY YFTFQVLSQW EICLSIVSSS RGQVRRSLGF CDTTNKGLFQ VVSGGMVLQL QQGDQVWVEK DPKKGHIYQG SEADSVFSGF LIFPSA (1-245 aa encoded by B C030153)
靶标信息
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: complement C1q chain A; Complement C1q subcomponent subunit A; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain
基因别名: AI255395; C1q; C1QA
UniProt ID: (Human) P02745, (Rat) P31720, (Mouse) P98086
Entrez Gene ID: (Human) 712, (Rat) 298566, (Mouse) 12259
