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Proteintech
C4orf49 Polyclonal Antibody
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产品信息
22569-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C4orf49 Fusion Protein Ag16552 (1-240 aa encoded by BC104174)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MYLRRAVSK TLALPLRAPP NPAPLGKDAS LRRMSSNRFP GSSGSNMIYY LVVGVTVSAG GYYAYKTVTS DQAKHTEHKT NLKEKTKAEI HPFQGEKENV AETEKASSEA PEELIVEAEV VDAEESPSAT VVVIKEASAC PGHVEAAPET TAVSAETGPE VTDAAARETT EVNPETTPEV TNAALDEAVT IDNDKDTTKN ETSDEYAELE EENSPAESES SAGDDLQEEA SVGSEAASAQ G (1-240 aa encoded by BC104174)
靶标信息
MGARP plays a role in the trafficking of mitochondria along microtubules. It regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. It participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. It also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CESP-1; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; Protein MGARP
基因别名: 4930583H14Rik; AI195347; C4orf49; CESP-1; CESP1; GS3582; HUMMR; MGARP; OSAP; Qsap
UniProt ID: (Human) Q8TDB4, (Mouse) Q8VI64
Entrez Gene ID: (Human) 84709, (Mouse) 67749
protein targeting to mitochondrion
anterograde axonal transport
retrograde axonal transport
positive regulation of mitochondrion organization
axonal transport of mitochondrion
cellular response to steroid hormone stimulus
cellular response to hypoxia
cellular response to gonadotropin-releasing hormone
regulation of mitochondrion organization
