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Invitrogen
C8orf4 Polyclonal Antibody
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产品信息
PA5-55538
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human C8orf4
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: AKRSHQAIIM STSLRVSPSI HGYHFDTASR KKAVGNIFEN TDQESLERLF RNSGDKKAEE RAKIIFAIDQ DVEEKTRALM ALKKRTKDKL FQFLKLRKYS IKVH
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
靶标信息
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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