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Invitrogen
CABLES1 Polyclonal Antibody
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产品信息
PA5-66663
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human CABLES1
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: TVSYTQFLLPT NAFGARRNTI DSTSSFSQFR NLSHRSLSIG RASGTQGSLD TGSDLGDFMD YD
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 84%.
靶标信息
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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