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Proteintech
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Immunogen sequence: TQFSETKQR ESQLMREQRV RFLSNASTLA SFSEPGSCYE ELLKYLVYIL RKAARRLAQV SRAAGVRVGL LSSPAPLGGQ ETQPSSSCSR SHRRLSVHHL VHHHHHHHHH YHLGNGTLRA PRASPEIQDR DANGSRRLML PPPSTPALSG APPGGAESVH SFYHADCHLE PVRCQAPPPR SPSEASGRTV GSGKVYPTVH TSPPPETLKE KALVEVAASS GPPTLTSLNI PPGPYSSMHK LLETQSTGAC QSSCKISSPC LKADSGACGP DSCPYCARAG AGEVELADRE MPDSDSEAVY EFTQDAQHSD LRDPHSRRQR SLGPDAEPSS VLAFWRLICD TFRKIVDS (396-742 aa encoded by BC110995)
Voltage-dependent Ca2+ channels mediate Ca2+ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca2+-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an alpha-1 subunit, an intracellular beta subunit, a disulfide linked alpha-2/delta subunit and a transmembrane gamma subunit. Ca2+ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca2+ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca2+ current types. T-type Ca2+ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calcium channel, voltage-dependent, T type, alpha 1G subunit; CaV T1; Cav3 1; cav3 1c; Cav3.1c; MGC117234; NBR13; voltage-dependent calcium channel alpha 1G subunit, isoform 11; voltage-dependent T-type calcium channel alpha 1G subunit; Voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1
基因别名: [a]1G; a1G; alpha-1G; Ca(V)T.1; CACNA1G; Cav3.1; Cav3.1d; KIAA1123; mKIAA1123; NBR13; SCA42
UniProt ID: (Human) O43497
Entrez Gene ID: (Human) 8913, (Rat) 29717, (Mouse) 12291