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Invitrogen
CALCOCO1 Polyclonal Antibody
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CALCOCO1 Antibody (PA5-121163) in WB
Western blot analysis of CALCOCO1 in extracts of various cell lines. Samples were incubated with CALCOCO1 Polyclonal antibody (Product # PA5-121163) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-121163
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 462-691 of human CALCOCO1 (NP_065949.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.41 mg/mL
规格
41 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HeLa, 293T, MCF7, A-549, Mouse lung, Mouse heart, Mouse thymus. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: LVQLSESKRE LTELRSALRV LQKEKEQLQE EKQELLEYMR KLEARLEKVA DEKWNEDATT EDEEAAVGLS CPAALTDSED ESPEDMRLPP YGLCERGDPG SSPAGPREAS PLVVISQPAP ISPHLSGPAE DSSSDSEAED EKSVLMAAVQ SGGEEANLLL PELGSAFYDM ASGFTVGTLS ETSTGGPATP TWKECPICKE RFPAESDKDA LEDHMDGHFF FSTQDPFTFE
靶标信息
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/beta-catenin signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium-binding and coiled-coil domain-containing protein 1; Calphoglin; Coiled-coil coactivator protein; coiled-coil transcriptional coactivator; granule cell antiserum positive 11; GRIP1-interacting protein; Sarcoma antigen NY-SAR-3
基因别名: 1810009B06Rik; CALCOCO1; CocoA; Gcap11; KIAA1536; mKIAA1536; PP13275; UNQ2436/PRO4996
UniProt ID: (Mouse) Q8CGU1
Entrez Gene ID: (Mouse) 67488
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
beta-catenin binding
protein C-terminus binding
ligand-dependent nuclear receptor transcription coactivator activity
sequence-specific DNA binding
transcription regulatory region DNA binding
armadillo repeat domain binding
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