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Immunogen sequence: MMVLKVEELV TGKKNGNGEA GEFLPEDFRD GEYEAAVTLE KQEDLKTLLA HPVTLGEQQW KSEKQREAEL KKKKLEQRSK LENLEDLEII IQLKKRKKYR KTKVPVVKEP EPEIITEPVD VPTFLKAALE; Positive Samples: SW480, HepG2, Jurkat, Mouse blood vessel, Mouse heart, Mouse lung, Rat heart, Rat lung; Cellular Location: Nucleus
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; ankyrin-like repeat protein; Cardiac adriamycin-responsive protein; Cardiac ankyrin repeat protein; cardiac responsive adriamycin protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1; muscle ankyrin repeat protein
基因别名: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; Crap; CVARP; HA1A2; MARP; MARP1; MCARP
UniProt ID: (Human) Q15327, (Mouse) Q9CR42, (Rat) Q8R560
Entrez Gene ID: (Human) 27063, (Mouse) 107765, (Rat) 27064
