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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化 (IHC) |
1:200-1:500 | - |
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human CASC4 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.05 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2639303 |
Immunogen sequence: DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF FDENESPVDP QHGSKLADYN GDDG
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%.
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer susceptibility candidate gene 4 protein; CASC4; gene associated with HER-2/neu overexpression; Golgi membrane protein 2; Protein GOLM2
基因别名: CASC4; GOLM2; H63; UNQ2573/PRO6308
UniProt ID: (Human) Q6P4E1
Entrez Gene ID: (Human) 113201
