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Invitrogen
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Immunogen sequence: AYKIHLPETV EQLRKFNARR KLKGAVLAAV SSHKFNSFYG DPPEELPDFS EDPTSSGAVS QVLDSLEEIH ALTDCSEKDL DFLHSVFQDQ HLHTLLDLYD KINTKSSPQI RNPPSDAVQR AKEVLEEISC YPENNDAKE
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 96%.
CASK is a calcium/calmodulin-dependent serine protein kinase which is a MAGUK (membrane-associated guanylate kinase) protein family member. CASK is a scaffold protein and the encoded protein is located at synapses in the brain. CASK associates with FG syndrome 4, mental retardation, microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. CASK functions as a cytoskeletal membrane scaffold that coordinates signal transduction pathways within the cortical cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。