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产品信息
PA5-50373
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to residues near the C terminal of human cation channel, sperm associated 4 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
2.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635826 |
产品详细信息
The antibody detects endogenous levels of total CATSPER4 protein.
靶标信息
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of thecation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cation channel sperm-associated protein 4; cation channel, sperm associated 4; CatSper4; CTSR4; ion channel CatSper4
基因别名: CATSPER4
UniProt ID: (Human) Q7RTX7
Entrez Gene ID: (Human) 378807
multicellular organism development
neuronal action potential
sperm motility
response to progesterone
regulation of ion transmembrane transport
sperm-egg recognition
sodium ion transmembrane transport
sperm capacitation
regulation of postsynaptic membrane potential
calcium ion transmembrane transport
membrane depolarization during action potential
