Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
CBFA2T3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
17190-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CBFA2T3 Fusion Protein Ag9265 (167-615 aa encoded by BC062624)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: KRRTPDRTK ENGSDRDPLH PQRYSPSNGP PQPTPPPHYR LEDIAMAHHF RDAYRHPDPR ELRERHRPLV VPGSRQEEVI DHKLTEREWA EEWKHLNNLL NCIMDMVEKT RRSLTVLRRC QEADREELNH WARRYSDAED TKKGPAPAAA RPRSSSAGPE GPQLDVPREF LPRTLTGYVP EDIWRKAEEA VNEVKRQAMS ELQKAVSDAE RKAHELITTE RAKMERALAE AKRQASEDAL TVINQQEDSS ESCWNCGRKA SETCSGCNAA RYCGSFCQHR DWEKHHHVCG QSLQGPTAVV ADPVPGPPEA AHSLGPSLPV GAASPSEAGS AGPSRPGSPS PPGPLDTVPR (167-615 aa encoded by BC062624)
靶标信息
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: core-binding factor, runt domain, alpha subunit 2; translocated to, 3; Eight twenty one protein 2; ETO/MTG8-related protein ETO-2; hMTG16; MTG16HEL; MTG8-related gene 2; MTG8-related protein 2; myeloid translocation gene 8 and 16b; Myeloid translocation gene on chromosome 16 protein; myeloid translocation gene-related protein 2; Protein CBFA2T3; Protein ETO-2; translocated to, 3; Zinc finger MYND domain-containing protein 4
基因别名: A630044F12Rik; AI465270; AW229127; CBFA2T3; Cbfa2t3h; ETO-2; ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4
UniProt ID: (Human) O75081, (Mouse) O54972
Entrez Gene ID: (Human) 863, (Mouse) 12398, (Rat) 361431
response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
cell differentiation
negative regulation of nucleic acid-templated transcription
positive regulation of transcription from RNA polymerase II promoter
