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Proteintech
CBLB Monoclonal Antibody (2D3A2)
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产品信息
66353-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
2D3A2
抗原
CBLB Fusion Protein Ag18757 (1-352 aa encoded by BC032851)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MANSMNGRN PGGRGGNPRK GRILGIIDAI QDAVGPPKQA AADRRTVEKT WKLMDKVVRL CQNPKLQLKN SPPYILDILP DTYQHLRLIL SKYDDNQKLA QLSENEYFKI YIDSLMKKSK RAIRLFKEGK ERMYEEQSQD RRNLTKLSLI FSHMLAEIKA IFPNGQFQGD NFRITKADAA EFWRKFFGDK TIVPWKVFRQ CLHEVHQISS GLEAMALKST IDLTCNDYIS VFEFDIFTRL FQPWGSILRN WNFLAVTHPG YMAFLTYDEV KARLQKYSTK PGSYIFRLSC TRLGQWAIGY VTGDGNILQT IPHNKPLFQA LIDGSREGFY LYPDGRSYNP DLTGLCEPTP HDH (1-352 aa encoded by BC032851)
靶标信息
This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Cas-Br-M (murine) ectropic retroviral transforming sequence b; Casitas B-lineage lymphoma b; Casitas B-lineage lymphoma proto-oncogene b; Cbl proto-oncogene B, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase B; E3 ubiquitin-protein ligase CBL-B; RING finger protein 56; RING-type E3 ubiquitin transferase CBL-B; SH3-binding protein CBL-B; Signal transduction protein CBL-B
基因别名: AI429560; AI851073; Cbl-b; CBLB; Nbla00127; RNF56
UniProt ID: (Human) Q13191, (Rat) Q8K4S7, (Mouse) Q3TTA7
Entrez Gene ID: (Human) 868, (Pig) 100621690, (Rat) 171136, (Mouse) 208650
phosphotyrosine binding
ubiquitin-protein transferase activity
signal transducer activity
calcium ion binding
protein binding
zinc ion binding
ligase activity
protein kinase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
damaged DNA-binding protein
ligase
metabolite interconversion enzyme
protein polyubiquitination
NLS-bearing protein import into nucleus
signal transduction
cell surface receptor signaling pathway
response to gravity
response to hormone
regulation of signaling
positive regulation of T cell anergy
immune response
protein ubiquitination
intracellular signal transduction
T cell activation
positive regulation of protein catabolic process
negative regulation of alpha-beta T cell proliferation
negative regulation of T cell receptor signaling pathway
