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Peptide Sequence: SASLSNLHSL DRSTREVELG LEYGSPTMNL AGQSLKFENG QWIAETGVSG GVDRREVQRL RRRNQQLEEE NNLLRLKVDI LLDMLSESTA ESHLMEKELD ELRISRKRK
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
蛋白别名: ARPP-binding protein; chibby CTNNB1-mediated transcription inhibitor; chibby homolog 1; coiled-coil protein PIGEA-14; Cytosolic leucine-rich protein; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein, 14 kDa; Protein chibby homolog 1
基因别名: ARB1; C22orf2; CBY; CBY1; HRIHFB2025; HS508I15A; PGEA1; PIGEA-14; PIGEA14
UniProt ID: (Human) Q9Y3M2
Entrez Gene ID: (Human) 25776