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Proteintech
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Immunogen sequence: MHKRKGPPG PPGRGAAAAR QLGLLVDLSP DGLMIPEDGA NDEELEAEFL ALVGGQPPAL EKLKGKGPLP MEAIEKMASL CMRDPDEDEE EGTDEDDLEA DDDLLAELNE VLGEEQKASE TPPPVAQPKP EAPHPGLETT LQERLALYQT AIESARQAGD SAKMRRYDRG LKTLENLLAS IRKGNAIDEA DIPPPVAIGK GPASTPTYSP APTQPAPRIA SAPEPRVTLE GPSATAPASS PGLAKPQMPP GPCSPGPLAQ LQSRQRDYKL AALHAKQQGD TTAAARHFRV AKSFDAVLEA LSRGEPVDLS CLPPPPDQLP PDPPSPPSQP PTPATAPSTT EVPPPPRTLL EA (1-351 aa encoded by BC064981)
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5-HT1A receptor; Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; mental retardation, nonsyndromic, autosomal recessive, 3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
基因别名: AKI1; BC016188; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3; RGD1306108; Tape
UniProt ID: (Human) Q9H603, (Rat) Q66HA5, (Mouse) Q8K1A6
Entrez Gene ID: (Human) 54862, (Rat) 288908, (Mouse) 212139