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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide corresponding to residues in human CCBE1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2553979 |
This antibody detects endogenous protein at a molecular weight of 44 kDa.
Purity is >95% by SDS-PAGE.
The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregulation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 results in changes in cell adhesion and mobility due to its characterization as an extracellular protein. There are three named isoforms of CCBE1 which are produced as a result of alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: collagen and calcium binding EGF domains 1; Collagen and calcium-binding EGF domain-containing protein 1; FLJ30681; Full of fluid protein homolog; MGC50861
基因别名: 4933426F18Rik; 9430093N24Rik; CCBE1; HKLLS1; KIAA1983; mKIAA1983; RGD1307670; UNQ1921/PRO4395
UniProt ID: (Human) Q6UXH8, (Mouse) Q3MI99
Entrez Gene ID: (Human) 147372, (Mouse) 320924, (Rat) 361341
