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Proteintech
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Immunogen sequence: MDEDGLPLM GSGIDLTKVP AIQQKRTVAF LNQFVVHTVQ FLNRFSTVCE EKLADLSLRI QQIETTLNIL DAKLSSIPGL DDVTVEVSPL NVTSVTNGAH PEATSEQPQQ SSTQDSGLQE SEVSAENILT VAKDPRYARY LKMVQVGVPV MAIRNKMISE GLDPDLLERP DAPVPDGESE KTVEESSDSE SSFSD (1-194 aa encoded by BC010889)
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coiled-coil domain-containing protein 53; WASH complex subunit 3
基因别名: AD-016; CCDC53; CGI-116; WASHC3; x0009
UniProt ID: (Human) Q9Y3C0
Entrez Gene ID: (Human) 51019