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PA1-31120 detects CCKBR from human samples.
PA1-31120 has been successfully used in immunohistochemistry (paraffin tissue), Western blot applications.
The PA1-31120 immunogen is: Poly Lysin conjugated synthetic peptide: VHRWPSARVRQTWS, corresponding to amino acids 206-219 of Human CCKBR.
CCKBR is a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR has been reported in brain, colon, pancreas, stomach, thyroid, and various cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。