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Abnova
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Sequence of this protein is as follows: MKVSVAALSC LMLVTALGSQ ARVTKDAETE FMMSKLPLEN PVLLDMLWRR KIGPQMTLSH AAGFHATSAD CCISYTPRSI PCSLLESYFE TNSECSKPGV IFLTKKGRRF CANPSDKQVQ VCVRMLKLDT RIKTRKN
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。