应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
0.1-0.5 µg/mL | - |
免疫组化(石蜡) (IHC (P)) |
0.5-1 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
1-5 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
E.coli-derived mouse CCL6 recombinant protein (Position: G22-A116). |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
500 µg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS with 4mg trehalose |
内含物 |
0.05mg sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2807340 |
Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Chemokine(C-C motif) ligand 6(CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin(e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced. CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-C motif chemokine 6; CC chemokine C10; CCL6(22-95); CCL6(23-95); chemokine ligand 6; Protein C10; small inducible cytokine A6; Small-inducible cytokine A6
基因别名: C10; Ccl6; MRP-1; Scay6; Scya6
UniProt ID: (Mouse) P27784, (Rat) Q68FP3
Entrez Gene ID: (Mouse) 20305, (Rat) 287910
分子生物学功能:
cytokine
intercellular signal molecule