FIGURE: 1 / 1
Recommended positive controls: Mouse lymph nodes or small intestine..
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.
Protein Aliases: C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR-10; Chemokine C-C receptor 9; G protein-coupled receptor 2; G-protein coupled receptor 2; MGC151420; RP23-281C18.3
Gene Aliases: Ccr10; Cmkbr9; Gpr2
UniProt ID: (Mouse) Q9JL21
Entrez Gene ID: (Mouse) 12777