Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
流式细胞分析 (Flow) |
4 µL / 100 µL whole blood or 10^6 cells | 查看1篇已发表文章 1篇已发表文章 |
产品规格 | |
---|---|
种属反应 |
Human, Rat |
已发表种属 |
Rat |
宿主/亚型 |
Mouse / IgG2a |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
MEM-226 |
抗原 |
Recombinant Vaccinia virus containing the human CD105 cDNA |
偶联物 |
Alexa Fluor™ 488
|
激发/发射光谱 |
499/520 nm 查看光谱 |
形式 |
Liquid |
纯化类型 |
Size-exclusion chromatography |
保存液 |
PBS, pH 7.4, with 0.2% BSA |
内含物 |
15mM sodium azide |
保存条件 |
4° C, store in dark, DO NOT FREEZE! |
RRID |
AB_2539494 |
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
蛋白别名: CD105; CD105 antigen; Endoglin; ORW
基因别名: END; ENG; HHT1; ORW1
UniProt ID: (Human) P17813
Entrez Gene ID: (Human) 2022, (Rat) 497010
分子生物学功能:
transmembrane signal receptor