Invitrogen

CD11c Monoclonal Antibody (N418), FITC

产品信息

MA5-16877

应用	建议稀释比	已发表文章
免疫组化 (IHC)	-	查看1篇已发表文章 1篇已发表文章
流式细胞分析 (Flow)	1:100	查看5篇已发表文章 5篇已发表文章
其他PubMed (Misc)	-	查看3篇已发表文章 3篇已发表文章

产品规格
种属反应	Mouse
已发表种属	Mouse
宿主/亚型	Armenian hamster / IgG
分类	Monoclonal
类型	Antibody
克隆号	N418
抗原	Mouse spleen dendritic cells.
偶联物	FITC Unconjugated
激发/发射光谱	查看光谱
形式	Liquid
浓度	0.1 mg/mL
纯化类型	Protein A
保存液	PBS with 1% BSA
内含物	0.09% sodium azide
保存条件	-20° C, Avoid Freeze/Thaw Cycles, store in dark
RRID	AB_2538355

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

靶标信息

CD11, along with CD18, form a heterodimer adhesion molecule. In particular, CD11 is composed of CD11a, CD11b and CD11c. CD11a is a leukocyte marker that is expressed in B and T lymphocytes, macrophages, monocytes, neutrophils, basophils and eosinophils. CD11b is primarily expressed by monocytes, macrophages, natural killer cells, some B and T-cells, and granulocytes. CD11c is expressed in monocytes, macrophages, natural killer cells, some granulocytes and less so in a subset of lymphocytes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Flow Cytometry

Panel Builder

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.

Scientific reports

Gardner PJ,Liyanage SE,Cristante E,Sampson RD,Dick AD,Ali RR,Bainbridge JW

MA516877 was used in flow cytometry to report the role of hypoxia inducible factors in myeloid trafficking during inflammation in a mouse model of human uveitis

Mon Jan 23 00:00:00 EST 2017

Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.

The Journal of experimental medicine

Henry EK,Sy CB,Inclan-Rico JM,Espinosa V,Ghanny SS,Dwyer DF,Soteropoulos P,Rivera A,Siracusa MC

MA516877 was used in flow cytometry to find a role for Car enzymes in regulating mast cell lineage commitment

Mon Aug 22 00:00:00 EDT 2016

Loss of Gadkin Affects Dendritic Cell Migration In Vitro.

PloS one

Schachtner H,Weimershaus M,Stache V,Plewa N,Legler DF,Höpken UE,Maritzen T

MA5-16877 was used in flow cytometry to determine the affects of dendritic cell migration in vitro by loss of gadkin

Mon Jun 20 00:00:00 EDT 2016

Heat-killed Staphylococcus aureus reduces atherosclerosis by inducing anti-inflammatory macrophages.

Journal of internal medicine

Frodermann V,van Duijn J,van Puijvelde GH,van Santbrink PJ,Lagraauw HM,de Vries MR,Quax PH,Bot I,Foks AC,de Jager SC,Kuiper J

MA516877 was used in flow cytometry to test whether heat-killed Staphyloccocus aureus inhibits the development of atherosclerosis

Wed Jun 01 00:00:00 EDT 2016

The pathogenesis of severe fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: insights into the pathologic mechanisms of a new viral hemorrhagic fever.

Journal of virology

Liu Y,Wu B,Paessler S,Walker DH,Tesh RB,Yu XJ

MA5-16877 was used in immunohistochemistry to study severe fever with thrombocytopenia syndrome virus infection pathogenesis using a murine model

Sat Feb 01 00:00:00 EST 2014

CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1.

Infection and immunity

Charles E,Joshi S,Ash JD,Fox BA,Farris AD,Bzik DJ,Lang ML,Blader IJ

MA5-16877 was used in flow cytometry to test if upregulation of major histocompatibility complex class II and costimulatory molecules in the retina contributes to the regulation of CD4 T cells

Sun Aug 01 00:00:00 EDT 2010

Time-course expression of Toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP.

Journal of leukocyte biology

Gomariz RP,Arranz A,Abad C,Torroba M,Martinez C,Rosignoli F,Garcia-Gómez M,Leceta J,Juarranz Y

MA5-16877 was used in flow cytometry to study TLR2 and 4 expression in a trinitrobenzene sulfonic acid-induced colitis model of Crohn's disease

Mon Aug 01 00:00:00 EDT 2005

Dramatic increase in lymph node dendritic cell number during infection by the mouse mammary tumor virus occurs by a CD62L-dependent blood-borne DC recruitment.

Blood

Martín P,Ruiz SR,del Hoyo GM,Anjuère F,Vargas HH,López-Bravo M,Ardavín C

MA5-16877 was used in flow cytometry to investigate the origin and involvement of CD8alpha(-) and CD8alpha(+) DCs in antiviral immune responses in vivo.

Fri Feb 15 00:00:00 EST 2002

Concept of lymphoid versus myeloid dendritic cell lineages revisited: both CD8alpha(-) and CD8alpha(+) dendritic cells are generated from CD4(low) lymphoid-committed precursors.

Blood

Martín P,del Hoyo GM,Anjuère F,Ruiz SR,Arias CF,Marín AR,Ardavín C

MA5-16877 was used in flow cytometry to investigate the origin of CD8alpha(+) and CD8alpha(-) DCs.

Sun Oct 01 00:00:00 EDT 2000

生物信息学

蛋白别名: CD11 antigen-like family member C; CD11c; CD11C (p150) alpha polypeptide; complement receptor 4; Integrin alpha-X; integrin aX; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95

基因别名: AI449405; Cd11c; Cr4; Itgax; N418

UniProt ID: (Mouse) Q9QXH4

Entrez Gene ID: (Mouse) 16411

分子生物学功能: integrin

功能

cell adhesion integrin-mediated signaling pathway heterotypic cell-cell adhesion activated T cell proliferation defense response to virus positive regulation of protein targeting to mitochondrion

参与通路

metal ion binding

CD11c Monoclonal Antibody (N418), FITC

产品信息

MA5-16877

免疫组化 (IHC)

流式细胞分析 (Flow)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

克隆号

抗原

偶联物

激发/发射光谱

形式

浓度

纯化类型

保存液

内含物

保存条件

RRID

产品详细信息

靶标信息

How to use the Panel Builder

生物信息学

性能保障

随时为您服务

Brands

Shopping Tools

eSolutions

Support

我们的公司

Your items have has been added!