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Proteintech
CD122/IL-2RB Polyclonal Antibody
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产品信息
32546-1-AP
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein
偶联物
形式
Liquid
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: AVKNCSHLEC FYNSRANVSC MWSHEEALNV TTCHVHAKSN LRHWNKTCEL TLVRQASWAC NLILGSFPES QSLTSVDLLD INVVCWEEKG WRRVKTCDFH PFDNLRLVAP HSLQVLHIDT QRCNISWKVS QVSHYIEPYL EFEARRRLLG HSWEDASVLS LKQRQQWLFL EMLIPSTSYE VQVRVKAQRN NTGTWSPWSQ PLTFRTRPAD PMKE
靶标信息
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD122; High affinity IL-2 receptor subunit beta; IL-15 receptor beta chain; IL-2 receptor beta chain; IL-2 receptor subunit beta; IL-2/15 receptor-beta; IL-2R subunit beta; IL-2RB; interleukin 2 receptor, beta chain; Interleukin-2 receptor subunit beta; P70-75
基因别名: CD122; IL-15Rbeta; Il-2/15Rbeta; Il-2Rbeta; IL15Rbeta; Il2rb; IL2RBC; p70
UniProt ID: (Rat) P26896, (Mouse) P16297
Entrez Gene ID: (Rat) 25746, (Mouse) 16185
