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Invitrogen
CD123 Polyclonal Antibody
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CD123 Antibody (PA5-27454) in IHC (P)
CD123 Polyclonal Antibody detects IL3 Receptor alpha protein at cell membrane and cytoplasm in human esophageal cancer by immunohistochemical analysis. Sample: Paraffin-embedded human esophageal cancer. CD123 Polyclonal Antibody (Product # PA5-27454) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-27454
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 95 and 298 of Human IL3 Receptor alpha
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
规格
48 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA5-27454 targets IL3 Receptor alpha in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27454 immunogen is recombinant fragment corresponding to a region within amino acids 95 and 298 of Human IL3 Receptor alpha.
靶标信息
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. IL-3Ra is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. IL-3Ra is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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