GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells.
Arif S,Gomez-Tourino I,Kamra Y,Pujol-Autonell I,Hanton E,Tree T,Melandri D,Hull C,Wherrett DK,Beam C,Roep BO,Lorenc A,Peakman M
MHCD1428 was used in Immunocytochemistry-immunoflourescence to show that GAD-alum immunisation activates and propagates GAD-specific CD4 T cells with a distinctive bifunctional phenotype, the functional analysis of which might be important in understanding therapeutic responses.
Mon Jun 01 00:00:00 EDT 2020
Over-expression of PD-1 Does Not Predict Leukemic Relapse after Allogeneic Stem Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Jain P,Tian X,Cordes S,Chen J,Cantilena CR,Bradley C,Panjwani R,Chinian F,Keyvanfar K,Battiwalla M,Muranski P,Barrett AJ,Ito S
MHCD1428 was used in Flow cytometry/Cell sorting to analyse the relationship of leukaemia relapse with T-cell marker kinetics.
Fri Feb 01 00:00:00 EST 2019
Barcoding of Macaque Hematopoietic Stem and Progenitor Cells: A Robust Platform to Assess Vector Genotoxicity.
Molecular therapy. Methods & clinical development
Yabe IM,Truitt LL,Espinoza DA,Wu C,Koelle S,Panch S,Corat MAF,Winkler T,Yu KR,Hong SG,Bonifacino A,Krouse A,Metzger M,Donahue RE,Dunbar CE
MHCD1428 was used in Flow cytometry/Cell sorting to investigate the impact of different vector designs on the clonal behaviour of haematopoietic stem and progenitor cells during in vivo expansion.
Fri Dec 14 00:00:00 EST 2018
Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study.
Arthritis research & therapy
Bartlett DB,Willis LH,Slentz CA,Hoselton A,Kelly L,Huebner JL,Kraus VB,Moss J,Muehlbauer MJ,Spielmann G,Kraus WE,Lord JM,Huffman KM
MHCD1428 was used in Flow cytometry/Cell sorting to determine whether 10 weeks of a walking-based HIIT program would be associated with health improvements as measured by disease activity and aerobic fitness.
Thu Jun 14 00:00:00 EDT 2018
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.
Kim MY,Yu KR,Kenderian SS,Ruella M,Chen S,Shin TH,Aljanahi AA,Schreeder D,Klichinsky M,Shestova O,Kozlowski MS,Cummins KD,Shan X,Shestov M,Bagg A,Morrissette JJD,Sekhri P,Lazzarotto CR,Calvo KR,Kuhns DB,Donahue RE,Behbehani GK,Tsai SQ,Dunbar CE,Gill S
MHCD1428 was used in Flow cytometry/Cell sorting to illuminate a novel approach to antigen-specific immunotherapy by genetically engineering the host to avoid on-target, off-tumor toxicity.
Thu May 31 00:00:00 EDT 2018
T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
Gomez-Tourino I,Kamra Y,Baptista R,Lorenc A,Peakman M
MHCD1428 was used in Flow cytometry/Cell sorting to suggest that short CDR3s increase the potential for self-recognition, conferring heightened risk of autoimmune disease.
Mon Nov 27 00:00:00 EST 2017
Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women.
Journal of immunology (Baltimore, Md. : 1950)
Tanko RF,Soares AP,Müller TL,Garrett NJ,Samsunder N,Abdool Karim Q,Abdool Karim SS,Riou C,Burgers WA
MHCD1428 was used in Flow cytometry/Cell sorting to study the effect of antiretroviral therapy on B cells in HIV infection.
Wed Feb 01 00:00:00 EST 2017
Immunization with Ty21a live oral typhoid vaccine elicits crossreactive multifunctional CD8+ T-cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A, and S. Paratyphi B in humans.
Wahid R,Fresnay S,Levine MM,Sztein MB
MHCD1428 was used in Immunocytochemistry-immunoflourescence to suggest that Ty21a elicits multifunctional CMI responses against Salmonella that could be critical in clearing the infection.
Sun Nov 01 00:00:00 EDT 2015
Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.
Hoffmann J,Shmeleva EV,Boag SE,Fiser K,Bagnall A,Murali S,Dimmick I,Pircher H,Martin-Ruiz C,Egred M,Keavney B,von Zglinicki T,Das R,Todryk S,Spyridopoulos I
MHCD1428 was used in flow cytometry to study the incidence of coronary heart disease in cytomegalovirus-seropositive individuals.
Fri Jan 02 00:00:00 EST 2015
Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-α monotherapy.
Ilander M,Kreutzman A,Rohon P,Melo T,Faber E,Porkka K,Vakkila J,Mustjoki S
MHCD1428 was used in flow cytometry to examine the function of NK- and T-cells in order to understand how chronic myeloid leukemia patients maintain the treatment response after IFN-α discontinuation.
Wed Oct 15 00:00:00 EDT 2014
Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism.
Bennaceur K,Atwill M,Al Zhrany N,Hoffmann J,Keavney B,Breault D,Richardson G,von Zglinicki T,Saretzki G,Spyridopoulos I
MHCD1428 was used in flow cytometry and immunocytochemistry to study the effect of atorvastatin on telomerase activity in peripheral blood mononuclear cells and T-lymphocytes
Wed Oct 01 00:00:00 EDT 2014
Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners.
Journal of virology
Pala P,Serwanga J,Watera C,Ritchie AJ,Moodie Z,Wang M,Goonetilleke N,Birabwa E,Hughes P,Senkaali D,Nakiboneka R,Grosskurth H,Haynes B,McMichael A,Kaleebu P
MHCD1428 was used in flow cytometry to characterize T cell responses of HIV-exposed, yet persistently uninfected individuals.
Thu Aug 01 00:00:00 EDT 2013
Unexpected heterogeneity of multifunctional T cells in response to superantigen stimulation in humans.
Clinical immunology (Orlando, Fla.)
McArthur MA,Sztein MB
MHCD1428 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which Staphylococcal enterotoxin B and other superantigens cause toxic shock syndrome.
Fri Feb 01 00:00:00 EST 2013
Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization.
McArthur MA,Sztein MB
MHCD1428 was used in flow cytometry to explore the multifunctional IL-17A responses against S. Typhi antigens in T memory subsets.
Tue Oct 02 00:00:00 EDT 2012
Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis.
Aurelius J,Thorén FB,Akhiani AA,Brune M,Palmqvist L,Hansson M,Hellstrand K,Martner A
MHCD1428 was used in Flow cytometry/Cell sorting to suggest a novel mechanism by which monocytic AML cells evade cell-mediated immunity.
Thu Jun 14 00:00:00 EDT 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
MHCD1428 was used in flow cytometry to develop and validate a novel system for high throughput quantitation of autophagy in primary human leukocytes.
Sun Apr 01 00:00:00 EDT 2012
Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining.
Journal of immunology (Baltimore, Md. : 1950)
Clement M,Ladell K,Ekeruche-Makinde J,Miles JJ,Edwards ES,Dolton G,Williams T,Schauenburg AJ,Cole DK,Lauder SN,Gallimore AM,Godkin AJ,Burrows SR,Price DA,Sewell AK,Wooldridge L
MHCD1428 was used in flow cytometry to test if anti-CD8 Abs induce effector function.
Fri Jul 15 00:00:00 EDT 2011