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Immunogen sequence: HVSQLTWARH GESGSMAVFH QTQGPSYSES KRLEFVAARL GAELRNASLR MFGLRVEDEG NYTCLFVTFP QGSRSVDIWL RVLAKPQNTA EVQKVQLTGE PVPMARCVST GGRPPAQITW HSDLGGMPNT S
Positive Samples: LO2; Cellular Location: Cell membrane, Single-pass type I membrane protein
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
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蛋白别名: CD155; FLJ25946; NECL-5; nectin-like 5; Nectin-like protein 5; Poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1
基因别名: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; Necl-5; NECL5; PVR; PVS; Taa1; TAGE4
UniProt ID: (Human) P15151