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CD155 Antibody (PA5-96414) in WB
Western blot analysis of CD155 in various lysates. Samples were incubated with CD155 Polyclonal antibody (Product # PA5-96414) using a dilution of 1:400, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-96414
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human CD155.
偶联物
Unconjugated
形式
Liquid
浓度
3.82 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808216
产品详细信息
Immunogen sequence: HVSQLTWARH GESGSMAVFH QTQGPSYSES KRLEFVAARL GAELRNASLR MFGLRVEDEG NYTCLFVTFP QGSRSVDIWL RVLAKPQNTA EVQKVQLTGE PVPMARCVST GGRPPAQITW HSDLGGMPNT S
Positive Samples: LO2; Cellular Location: Cell membrane, Single-pass type I membrane protein
靶标信息
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD155; FLJ25946; NECL-5; nectin-like 5; Nectin-like protein 5; Poliovirus receptor; sCD112; soluble CD112; tumor-associated antigen 1
基因别名: 3830421F03Rik; CD155; D7Ertd458e; HVED; mE4; Necl-5; NECL5; PVR; PVS; Taa1; TAGE4
UniProt ID: (Human) P15151
Entrez Gene ID: (Human) 5817, (Mouse) 52118
single organismal cell-cell adhesion
cell migration
viral entry into host cell
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
cell recognition
adherens junction organization
susceptibility to natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
susceptibility to T cell mediated cytotoxicity
