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Invitrogen
CD179b Recombinant Rabbit Monoclonal Antibody (8H16L35)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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CD179b Antibody (702901) in ICC/IF
For immunofluorescence analysis, JM1 cells were fixed and permeabilized for detection of endogenous CD179b using Anti-CD179b Recombinant Rabbit Monoclonal Antibody (Product # 702901,1:100 dilution) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962), and Rhodamine Phalloidin (Product # R415, 1:300) was used for cytoskeletal F-actin (red) staining. Panel a-d)... View More
产品信息
702901
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8H16L35
抗原
Peptides corresponding to human CD179b [1) aa93-aa112 2) aa152-aa167]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2762380
产品详细信息
This antibody is predicted to react with Monkey, Cat, Pig, Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
The preB cell receptor, CD179b, is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation and differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda-5; IGLJ IGLL; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; Immunoglobulin-related protein 14.1; lambda5; Pre-B lymphocyte-specific protein-2
基因别名: 14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGLL1; IGO; IGVPB; VPREB2
UniProt ID: (Human) P15814
Entrez Gene ID: (Human) 3543
