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CD2/CD7 Antibody Cocktail, FITC, PE
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产品信息
0027S
产品规格
种属反应
Human
宿主/亚型
Mouse
分类
Cocktail
类型
Antibody
抗原
CD2 was derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with t lymphocytes activated by mixed lymphocyte culture. CD7 was derived from the hybridization of mouse P3-X63-Ag8.653 myeloma cells with spleen cells of BALB/c mice immunized with T-acute lymphoblastic leukemia (T-ALL) cells.
偶联物
形式
Liquid
纯化类型
Protein A/G
保存液
PBS with 0.2% carrier protein
内含物
0.08% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Flow Cytometry PBMC: Add 10 µL of MAB/10^6 PBMC in 100 µL PBS. Mix gently and incubate for 15 minutes at 2 to 8C. Wash twice with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze.
Flow Cytometry Whole Blood: Add10 µL of MAB/100 µL of whole blood. Mix gently and incubate for 15 minutes at room temperature 20C. Lyse the whole blood. Wash once with PBS and analyze or fix with 0.5% v/v of paraformaldehyde in PBS and analyze. See instrument manufacturer instructions for Lysed Whole Blood and Immunofluorescence analysis with a flow cytometer or microscope.
靶标信息
Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2CD2 antigen; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 surface antigen; CD7; CD7 antigen (p41); Erythrocyte receptor; GP40; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; p41 protein; Rosette receptor; surface antigen CD2 precursor; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen CD2 precursor; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; TP41; unnamed protein product
基因别名: CD2; CD7; GP40; LEU-9; LFA-2; SRBC; T11; Tp40; TP41
UniProt ID: (Human) P06729, (Human) P09564
Entrez Gene ID: (Human) 914, (Human) 924
adaptive immune response
immune system process
positive regulation of T cell cytokine production
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
interleukin-2-mediated signaling pathway
T cell activation
membrane raft polarization
apoptotic process
cell adhesion
cell surface receptor signaling pathway
natural killer cell activation
positive regulation of myeloid dendritic cell activation
positive regulation of interferon-gamma production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
heterotypic cell-cell adhesion
natural killer cell mediated cytotoxicity
regulation of T cell differentiation
cell-cell adhesion
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