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Proteintech
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Sequence of this protein is as follows: KETPPTVISG MLGGSVTFSL NISKDAEIEH IIWNCPPKAL ALVFYKKDIT ILDKGYNGRL KVSEDGYSLY MSNLTKSDSG SYHAQINQKN VILTTNKEFT LHIYEKLQKP QIIVESVTPS DTDSCTFTLI CTVKGTKDSV QYSWTREDTH LNTYDGSHTL RVSQSVCDPD LPYTCKAWNP VSQNSSQPVR IWQFCTGASR RKTAAGKTVV GILGEPVTLP LEFRATRATK NVVWVFNTSV ISQERRGAAT ADSRRKPKGS EERRVRTSDQ DQSLKISQLK MEDAGPYHAY VCSEASRDPS VRHFTLLVYK RLEKPSVTKS PVHMMNGICE VVLTCSVDGG GNNVTYTWMP LQNKAVMSQG KSHLNVSWES GEHLPNFTCT AHNPVSNSSS QFSSGTICSG PERNKR
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD229; Cell surface molecule Ly-9; Lymphocyte antigen 9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T-lymphocyte surface antigen Ly-9
基因别名: AI893573; CD229; Lgp100; Ly-9; Ly9; SLAMF3; T100
UniProt ID: (Mouse) Q01965
Entrez Gene ID: (Mouse) 17085