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Invitrogen
CD3/CD62L Antibody Cocktail, FITC, PE
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产品信息
MA1-12213
产品规格
宿主/亚型
Mouse
/ IgG1/IgG2a
分类
Cocktail
类型
Antibody
克隆号
M2AB, 1H3
抗原
human thymocytes and human peripheral blood T lymphocytes
偶联物
形式
Liquid
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Wet ice
RRID
产品详细信息
This antibody is a monoclonal mixture of FITC-conjugated CD3 (clone M2AB, isotype IgG1) and PE-conjugated CD62L (clone 1H3, isotype IgG2a).
靶标信息
T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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